Treatment of ocular surface squamous neoplasia with topical 1% 5-fluorouracil
نویسندگان
چکیده
Ocular surface squamous neoplasia (OSSN) is the most common type of ocular tumour. An eighty-year-old man with an elevated lesion in right eye was diagnosed to have OSSN. 1% topical 5-FU started as intermittent treatment. Examination during each visit showed consistent reduction size lesion. The patient complete regression no recurrence following treatment at 3 months from presentation. Tropical provides excellent prognosis cases
منابع مشابه
Topical 1% 5-fluorouracil in ocular surface squamous neoplasia: a long-term safety study.
BACKGROUND/AIMS The aim of this study was to evaluate the long-term corneal toxicity of topical chemotherapy with 1% 5-fluorouracil (5-FU) as a sole or adjuvant treatment of ocular surface squamous neoplasia (OSSN). METHODS Forty-one consecutive cases of OSSN were included in this prospective study. Patients underwent topical chemotherapy with 1% 5-FU four times/day for 4 weeks (one co...
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To cite: Pujari A. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2016218344 DESCRIPTION A 64-year-old male patient presented with fleshy lesion over the right temporal conjunctiva for the past 3 months with a gradual increase in size. History of trauma and pain was absent, and past history did not reveal any significant ocular/systemic morbidities. Right eye exa...
متن کاملtopical mitomycin c for partially excised ocular surface squamous neoplasia
purpose : to develop a guideline for the treatment of incompletely removed histopathologically documented ocular surface neoplasia (ossn) with mitomycin c (mmc). materials & methods : through an interventional case series, 17 eyes of 17 patients presented with incompletely removed ossn were treated according to a protocol using 2-3 alternate 7-day courses of mmc 0.04%. clinical recurrence was r...
متن کاملTopical 1% 5-fluoruracil as a sole treatment of corneoconjunctival ocular surface squamous neoplasia: long-term study
AIMS To report long-term clinical outcome of topical 1% 5-fluoruracil (5-FU) as a sole treatment of ocular surface squamous neoplasia (OSSN). METHODS 41 patients affected by OSSN were included. Each patient underwent full ophthalmological examination at baseline, with cytological or histological confirmation. Patients were treated by topical chemotherapy with 1% 5-FU four times a day for 4 we...
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AIM To evaluate the efficacy of topical 5-fluorouracil (5-FU) alone, without concurrent surgery or radiotherapy, for the treatment of conjunctival squamous cell carcinoma. METHODS Eight patients affected by conjunctival squamous cell carcinoma (three recurrent cases, three incompletely excised, and two untreated cases) were treated with 1% 5-FU eye drops. Topical 1% 5-FU was administered four...
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ژورنال
عنوان ژورنال: IP international journal of ocular oncology and oculoplasty
سال: 2023
ISSN: ['2581-5016', '2581-5024']
DOI: https://doi.org/10.18231/j.ijooo.2023.010